Yvan Saeys obtained his PhD in computer science from Ghent University. After spending time abroad at the University of the Basque Country (Spain) and the University of Lyon (France) he returned to Belgium and established the Data Mining and Modeling for Biomedicine (DAMBI) group at the VIB Center for Inflammation Research (IRC) in Gent. As of 2015, he is a professor at Ghent University and a principal investigator (group leader) at VIB, where he is heading an interdisciplinary research team of 21 people, consisting of mathematicians, computer scientists, engineers and bioinformaticians. The Saeys lab studies the design and application of novel data mining and machine learning techniques for high-dimensional single-cell omics data, including methods to model cell developmental trajectories and intercellular communication. At the methodological level, the lab studies the robustness and interpretability of machine learning models.